Just like any other F1 cross..... If you are willing to keep them all (or have help keeping them all), accept that none of the pups will be created equal, pick out the one or two that express your desired mix of traits at maturity, and cull the rest, why not give it a shot?
Don't expect too much, be willing to accept failure, and go for it.
I do have to agree though, that your best method of achieving your end result goal is buying a dog or pup from lines proven to express the traits you desire....... Much higher chance of success that way.
Steve
