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Author Topic: ivamec o.d. question?  (Read 2423 times)
Reuben
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« Reply #20 on: May 29, 2013, 07:11:53 am »

I knew ivomec killed microfilaria...and I thought that the normal monthly dose would keep the microfilaria killed off until the adult worms died off...and I also thought that several high doses of ivomec would kill the adult worms as well...I reckon I have been wrong for many years on that one...  Undecided

but I will say this...back in 1983 a Foster and Smith catalog put out a recipe to kill heartworms in a dog...they said that it was used extensively in Europe and Australia and that it worked and it only costs a few dollars to do so...I had the catalog saved in my locker at work and a few years later I needed to treat a dog and I thought I had misplaced the catalog...I called Foster and Smith to see if they would send me another catalog from the 1983 issue or to at least give me the recipe over the phone...Well, the Vet paused for a moment and then asked me who I was...then he says that he can not send out that catalog and he can not give the recipe because the veterinary association (some organization) threatened to pull their practicing liscenses because this treatment was not FDA approved...long story short I went thru all my dog magazine storage places and found the catalog...I still have it somewhere around here but that recipe is now burned in my brain...  Wink

I have treated 7 or 8 dogs with this treatment and one dog that the vet said it should be put down because it would not make it...back then the only treatment was with arsnic back then and some times the cure was worse than the heartworms...not to mention it cost an arm and a leg to put a dog thru that treatment...
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justincorbell
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« Reply #21 on: May 29, 2013, 09:50:40 am »

I knew ivomec killed microfilaria...and I thought that the normal monthly dose would keep the microfilaria killed off until the adult worms died off...and I also thought that several high doses of ivomec would kill the adult worms as well...I reckon I have been wrong for many years on that one...  Undecided

but I will say this...back in 1983 a Foster and Smith catalog put out a recipe to kill heartworms in a dog...they said that it was used extensively in Europe and Australia and that it worked and it only costs a few dollars to do so...I had the catalog saved in my locker at work and a few years later I needed to treat a dog and I thought I had misplaced the catalog...I called Foster and Smith to see if they would send me another catalog from the 1983 issue or to at least give me the recipe over the phone...Well, the Vet paused for a moment and then asked me who I was...then he says that he can not send out that catalog and he can not give the recipe because the veterinary association (some organization) threatened to pull their practicing liscenses because this treatment was not FDA approved...long story short I went thru all my dog magazine storage places and found the catalog...I still have it somewhere around here but that recipe is now burned in my brain...  Wink

I have treated 7 or 8 dogs with this treatment and one dog that the vet said it should be put down because it would not make it...back then the only treatment was with arsnic back then and some times the cure was worse than the heartworms...not to mention it cost an arm and a leg to put a dog thru that treatment...

Mr. Reuben, I lost the best dog ive ever owned to heartworms/ arsenic treatment, if you get a spare moment please pm this treatment method in case it is needed in the future.......I promise I won't tell the veterinary association about it!  Grin
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« Reply #22 on: May 29, 2013, 02:33:06 pm »

I knew ivomec killed microfilaria...and I thought that the normal monthly dose would keep the microfilaria killed off until the adult worms died off...and I also thought that several high doses of ivomec would kill the adult worms as well...I reckon I have been wrong for many years on that one...  Undecided

but I will say this...back in 1983 a Foster and Smith catalog put out a recipe to kill heartworms in a dog...they said that it was used extensively in Europe and Australia and that it worked and it only costs a few dollars to do so...I had the catalog saved in my locker at work and a few years later I needed to treat a dog and I thought I had misplaced the catalog...I called Foster and Smith to see if they would send me another catalog from the 1983 issue or to at least give me the recipe over the phone...Well, the Vet paused for a moment and then asked me who I was...then he says that he can not send out that catalog and he can not give the recipe because the veterinary association (some organization) threatened to pull their practicing liscenses because this treatment was not FDA approved...long story short I went thru all my dog magazine storage places and found the catalog...I still have it somewhere around here but that recipe is now burned in my brain...  Wink

I have treated 7 or 8 dogs with this treatment and one dog that the vet said it should be put down because it would not make it...back then the only treatment was with arsnic back then and some times the cure was worse than the heartworms...not to mention it cost an arm and a leg to put a dog thru that treatment...

Mr. Reuben, I lost the best dog ive ever owned to heartworms/ arsenic treatment, if you get a spare moment please pm this treatment method in case it is needed in the future.......I promise I won't tell the veterinary association about it!  Grin
[/quote
Please P.M it me me also.   I would like to know.
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Reuben
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« Reply #23 on: May 29, 2013, 02:41:35 pm »

I am at work right now...will pm later...
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justincorbell
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« Reply #24 on: May 29, 2013, 03:32:24 pm »

Thank you sir.
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« Reply #25 on: June 03, 2013, 06:45:28 am »

Interesting stuff. thanks for sharing. I wish i was a vet. I'de love it so much.
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Hogsnatchers
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« Reply #26 on: June 03, 2013, 06:52:58 am »

Please add me to that pm list if you don't mind Mr Reuben I'd greatly appreciate it

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setxhogdogs
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« Reply #27 on: June 03, 2013, 09:32:52 am »

Please pm me the recipe as well Mr. Reuben


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bigthickethogdogs
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« Reply #28 on: June 03, 2013, 09:45:08 am »

Please add me to that pm list if you don't mind Mr Reuben I'd greatly appreciate it

add me as well if you dont mind 
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« Reply #29 on: June 03, 2013, 12:58:15 pm »

All of you should have the treatment in a PM, I had a moment and I know Mr. Reuben gets busy with work so I figured i'd forward it to ya'll, hope you don't mind Mr. Reuben.
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Reuben
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« Reply #30 on: June 03, 2013, 01:18:06 pm »

All of you should have the treatment in a PM, I had a moment and I know Mr. Reuben gets busy with work so I figured i'd forward it to ya'll, hope you don't mind Mr. Reuben.

Thanks Justin...I appreciate it very much...
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Training dogs is not about quantity, it's more about timing, the right situations, and proper guidance...After that it's up to the dog...
A hunting dog is born not made...
justincorbell
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« Reply #31 on: June 03, 2013, 01:38:57 pm »

All of you should have the treatment in a PM, I had a moment and I know Mr. Reuben gets busy with work so I figured i'd forward it to ya'll, hope you don't mind Mr. Reuben.

Thanks Justin...I appreciate it very much...

yes sir Mr. Reuben, once again thanks for sharing your knowledge!
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« Reply #32 on: June 03, 2013, 01:39:29 pm »

I have always heard the same thing about ivomec killing off the microfilariae in the bloodstream. I got a young plott in about a year & 1/2 old & first of the month, gave all the dogs there ivomec. I ended up giving this dog 1 1/2 cc because he looked wormy. Next day he was lethargic & did not eat. The following morning I went out to check on the dogs & he was dead. Took him to the vet for a autopsy & when they cut him open he had heartworms but what killed him was one of the worms came out of the heart into his lungs & he strangled. Vet said it was probably the ivomec that caused that heartworm to vacate the heart & move. Called the previous owner & he told me he never had the dog on any type of heartworm preventive. Could not believe it. Only a year 1/2 old & this dog had a fistfull of heartworms in his heart.
  Every dog on my place from 3 months old gets his dose of ivomec on the first of the month. Never had any other problems.
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Bayou Cajun Plotts
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« Reply #33 on: June 03, 2013, 02:06:24 pm »

Hey Rueben or Justin, can you pm me the treatment as well.
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Reuben
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« Reply #34 on: June 05, 2013, 11:50:25 am »


Brand Names:
•Tramisole
• Levasol
 
Drug Name:

levamisole
 
•Family: Imidothiazole
•Treatment & Control of: Lungworms, roundworms.
•Goat dose: ◦ Injection: Tramisol injectable 13.65% is given SQ at the rate of 2ml/100lbs.
◦Oral: The oral sheep oblets: 2 tablets/100 lbs.

•Milk withholding time: 4 days
•Notes: ◦ Levamisole is very effective against lung worms.
◦Safe in pregnant animals.
◦ There has been reported toxicity with this wormer if overdosed, so be sure to weigh your goats and administer the correct amount for each animal. Do not overdose.
◦ Do to the possibility of death if over dosed, I personally avoid using this wormer if at all possible.

Levasole probably is no more...so LEVASOL and TRAMISOLE or what you need to look for...back when I used this wormer the pill wormed a forty pound goat and the procedure called for the same weight of the dog...so my feeling is that these wormers should be used the same...the message above says that this wormer is toxic but the dogs might show symptoms but the dogs I treated never showed any reaction to the medication...Foster and Smith said the same thing...this wormer can also be used for hooks and rounds but I never have...
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Training dogs is not about quantity, it's more about timing, the right situations, and proper guidance...After that it's up to the dog...
A hunting dog is born not made...
justincorbell
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« Reply #35 on: June 05, 2013, 12:30:25 pm »

LOL .........reckon it was probly just easier to do it that way in the first place Mr. Reuben!
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« Reply #36 on: June 05, 2013, 09:58:00 pm »

I've never heard of a dog overdosing on it but I wormed one of my pits with it and he brokeout in big sores all over. I had a friend of mine look at him and he said that it affected him differently than my cur dogs because some of them have sensitive skin. Anybody have any other thoughts?
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Cajun
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« Reply #37 on: June 05, 2013, 11:21:48 pm »

I have heard you are never supposed to give the Collie breeds ivomec. Either allergic or some other reaction to it. Anybody else heard of this.
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Bayou Cajun Plotts
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« Reply #38 on: June 05, 2013, 11:42:14 pm »

   here you go Cajun .

  SIDE EFFECTS

Side effects are not a concern with the extremely low doses used in commercially marketed heartworm preventives.

Problems may arise when higher doses, such as those used against skin mites, are employed but even then, side effects generally do not occur with any anti-mange doses of ivermectin except in animals with genetic sensitivity. Such individuals are usually Collies, Shetland sheepdogs, Australian shepherds, and Old English sheepdogs, though some individual animals that are not members of these sensitive breeds may also be prone to side effects. Very low test doses are often recommended to identify thes individuals regardless of their breed. Alternatively, a blood test is available to test for genetic sensitivity (see below).

Collies with ivermectin sensitivity have been found to have a mutant gene for what is called the "P-glycoprotein." The P-glycoprotein has been studied largely because overexpression of this protein (i.e. having more of it than normal) results poor function of chemotherapy drugs in the treatment of cancer. The P-glycoprotein appears to be involved in keeping drugs out of certain body tissues. Having excess P-glycoprotein keeps chemotherapy drugs from reaching the tumor. When it comes to ivermectin sensitivity the problem is the opposite: mutant or non-functional P-glycoprotein leads to failure to keep certain drugs out of the central nervous system, allowing them access to sensitive tissue. Ivermectin side effects stem from ivermectin entering the central nervous system.

Approximately 35% of Collies have a genetic mutation creating a non-functional P-glycoprotein. This allows for ivermectin doses that would normally be blocked from the central nervous system to gain access to it. Other herding breeds as listed above also have a tendency to express this mutation. There is now a test for P-glycoprotein mutation so that ivermectin sensitive dogs can be identified. This is a DNA test using an oral swab. Test kits can be ordered directly from the Washington State University Veterinary School via

www.vetmed.wsu.edu/depts-vcpl

Heartworm preventive doses are so low that side effects are not produced even in ivermectin sensitive individuals.

Side effects of concern are: dilated pupils and drunken gait which can progress to respiratory paralysis and death if medication is not withdrawn and supportive care is not initiated
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« Reply #39 on: June 06, 2013, 04:13:02 pm »

Thanks Halfbreed, Knew I heard it somewhere.  All in all, ivomec is the most bang for your buck all things considering.
  I remember when they first started worming horses with it, & everybody started buying ivomec at the feed stores & worming their own horses. The vets did not like that so they started saying it would cause reactions to horses. I know I wormed alot of horses with it & never had a problem. Soon after is when they started coming out with zimectrin horse paste wormers & others with ivomec in them.
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